8-溴嘌呤核苷与亲核试剂在水溶液中,于400W,95℃微波辐射5min合成了10种8-取代嘌呤核苷,收率72%~92%,其结构经^1H NMR和^13C NMR表征。
8-Substituted purine nucleosides in yield of 72% - 92% were synthesized from 8-bromopurine nucleoside and nucleophilic reagent at 95 ℃ and 400 W under microwave irradiation for 5 min in water. The structures were characterized by ^1H NMR and ^13C NMR.