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中文摘要：
在室温条件下,以邻菲罗啉作为配体,无水氯化镍催化的Negishi偶联反应合成了一系列6位链状仲烷基取代的嘌呤化合物.该方法反应条件温和、原料易得、产物收率高.
英文摘要：
An efficient method for the synthesis of 6-acyclic secondary alkyl purines was developed via nickel-catalyzed Negishi cross-cupling of 6-chloropurines with acyclic secondary alkylzinc halides in the presence of phenanthroline at room temperature.The process gave good to excellent isolated yields under very mild conditions.
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