中文摘要：

目的揭示和量化分析体位变化对男性和女性桡动脉脉搏波的影响。方法选择20名健康学生,采用双路脉搏信号采集设备,分别测量受试者在0度、45度、90度倾斜床上的桡动脉脉搏波,并计算其基本的血流动力学参数和相应的双弹性腔模型参数。采用配对t检验分析比较了不同体位下男性和女性的血流动力学参数。结果随着体位的升高（即受试者随倾斜床坐0度到45度再到90度的变化）男性和女性的心率（HR）和心内膜下心肌活力率（SEVR）均显著变大（P〈0.05）;男性和女性的桡动脉下降时间（Tdown）显著减小（P〈0.05）;其他血流动力学参数随体位变化不显著（P〉0.05）;随着体位的升高男性和女性的主动脉顺应性（C1）和腹主动脉顺应性（C2）变小、外周阻力（R）变大。男性和女性的HR、R、u-L（ratio）具有统计学差异（P〈0.05）;男性和女性的K值、T（up）、Tdown、T（LVET）、LM-P（ratio）、d AI、SEVR、u-d（ratio）、C1、C2没有统计学差异（P〉0.05）。结论体位变化对桡动脉脉搏波存在明显影响,且对男性和女性血流动力学参数的影响有差异,应引起临床重视。

英文摘要：

Objective To reveal and quantitatively analyze the influence of postural changes on male and female radial pulse wave. Methods 20 healthy students were enrolled in this study to collect their radial pulse wave by using dual pulse signal acquisition equipment at the tilting bed with 0 degrees, 45 degrees, 90 degrees; and then, the basic hemodynamic parameters and the model parameters on dual Windkessel model were calculated. The hemodynamic parameters of male and female were analyzed and compared by paired t-test. Results The results showed that with the increase of body position（The subject along with tilt bed-from 0 degrees to 45 degrees and then to 90 degrees）both male and female heart rate（HR） and sub-endocardial myocardial viability rate（SEVR） were significant increased（P〈0.05）; radial artery pressure full time（Tdown） was significant decreased（P〉0.05）, however, other hemodynamic parameters did not change significantly with body position（P〉0.05）; both arterial compliance（C1） and abdominal aortic compliance（C2） became smaller with the increase of body position in male and female, peripheral resistance（R） became larger. HR, R, u-L（ratio） of male and female have statistical difference（P〈0.05）; there were no statistically significant differences in K value, T（up）, Tdown, T（LVET）, LM-P（ratio）, d AI, SEVR, u-d（ratio）, C1 and C2 between males and females（P〉0.05）. Conclusion Body position has an obvious influence on radial artery and there are differences between male and female hemodynamic parameters, which should be paid more attention in clinic.