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中文摘要：
作为一种细胞内重要的信使物质，钙离子在精子运动中发挥着重要作用。钙离子对精子运动的调控主要是通过精子质膜上相关的钙离子通道所介导，其中包括电压门控钙离子通道、环核苷酸门控通道、电压门控阳离子通道和瞬时感受器电位家族，这些通道的任何一个环节出现问题均可以导致精子活动力的下降。本文就近年来与精子运动相关的钙离子通道的研究进展进行了简要综述。
英文摘要：
As an important intracellular messenger, Ca^2＋ plays a major role in sperm motility. In spermatozoa, multiple Ca^2＋ -permeable channels have been identified in the plasma membrane of mammalian sperm, including voltage-gated Ca^2＋ channels （ Car channels）, cyclic nucleotide-gated channels （ CNGC）, cation channels of sperm （CatSper） and the transient receptor potential （TRP） family. As calcium regulation of sperm motility is mainly mediated by these calcium channels, any aberration of the channels can lead to the decline of sperm activities. Recent progress in the researches on the relationship between sperm motility and calcium-related ion channels is briefly reviewed in this article.
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同项目期刊论文
Differential expression of VASA gene in ejaculated spermatozoa from normozoospermic men and patients
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