目的探讨中药治疗狼疮性肾炎的用药规律。方法收集2000年至2013年中医治疗狼疮肾炎的文献,分析探讨中药治疗狼疮。肾炎的用药规律,并进行统计分析。结果56篇治疗狼疮性肾炎的文献中,涉及中药196味,累计使用1276次;使用频率超过1%的中药共29味,累计使用频次702次,累计频率55.02%;清热药、补虚药、活血化瘀药、利水渗湿药、收涩药5类药使用较多,累积频率达84.41%;清热药中以清热凉血药和清热解毒药为主,补虚药中以补气和补阴药为主。结论狼疮性肾炎多用清热药凉血解毒、补虚药益气养阴.兼以活血化瘀药、利水渗湿药、收敛药等共同治疗.
Objective: To explore the law of traditional Chinese medicine treating Lupus nephritis (LN). Methods: 56 papers concerning TCM treatment of LN from 2000 to 2013 were collected and an analysis of drug laws was made with statistical methods. Results: Among the literatures, 196 kinds of traditional Chinese herbs were involved and repeated 1276 times altogether in these papers. There were 29 TCM herbs used over 1% of usage frequency ,with the total number of 702 times altogether. The cumulative frequency of that was 55.02%. Five kinds of herbs whose cumulative frequency up to 84.41% Were commonly used for clearing heat,reinforcing deficiency,promoting blood circulation and removing stasis, removing dampness and promoting diuresis, and inducing astringency. Heat-clearing and blood-cooling, and heat-clearing and toxin detoxicating herbs were mainly used in heat-clearing medicine. On the other hand,invigorating qi and invigorating yin herbs were among the most frequent used reinforcing-deficiency medicine. Conclusion: Heat-clearing herbs for cooling blood and detoxifying,reinforcing-deficiency herbs for supplementing qi and nourishing ),in,blood-activating and stasis-eliminating herbs,removing dampness and promoting diuresis herbs, as well as astringent are Usually used treating Lupus nephritis.