整体观念是中医学理论的基本特征之一,阴平阳秘是中医学的核心内容,阴阳失调是疾病发生发展的基本病机,调整阴阳平衡是疾病治疗的总原则。现代免疫学表明,系统性红斑狼疮(SLE)中雌激素受体α(ERα)、雌激素受体β(ERβ)两者之间存在着对立制约、消长平衡、互根互用的关系。中医药通过调节ERα/ERβ间的"阴阳平衡",可以达到治疗系统性红斑狼疮的目的。
The overall concept was one of the basic features of the traditional Chinese medicine theory. The bal- ance between Yin and Yang is the core content of traditional Chinese Medicine. The unbalance between Yin and Yang is the basic pathogenesis of various diseases. Adjusting the balance between Yin and Yang is the general principle of the treatment of disease. The development of modern immunology proves that the relationship between ERα and ERβ is opposite constraint,fluctuation equilibrium and interaction. Chinese medicine regulates the Yin- Yang balance between ERα and ERβ ,so as to achieve the purpose of treating systemic lupus erythematosus.