中文摘要：

目的：通过对大鼠异食癖程度的观察来判断前庭皮质中前扣带回皮质（ACC）是否在（动病（MS）的产生中起到作用。方法：两组大鼠（对照组和ACC损毁组）接受2h双轴旋转刺激。结果：对照组在高岭土的摄食上产生了很大的差异（P〈0.05）,而ACC损毁组的摄取量却没有发生改变（P〉0.05）.后数据经Two-WayANOVA处理后显示同对照组比较,手术组的高岭土摄食量在旋转刺激后减少（P〈0.05）。结论：结合组织学证明损毁部位局限于ACC部位这一形态学依据,本研究结果提示ACC在正常神经网络通过参与前庭信息的处理,在MS发生上起到了重要的作用。

英文摘要：

Objective：The present work aims to examine whether the vestibular-cortex,anterior cingulate cortex（ACC）,plays a role in development of motion sickness（MS）in rat.Methods：Picaism is a symptom indicating motion sickness in rat which didn＇t have emesis response.Two groups of rats received a 2-hour double rotation exposure,with the experimental group being lesioned by electrolysis at ACC.Results：We observed that rotation stimulation induced a significant increase in kaolin intake in control group（P 0.05）,but not in experimental group（P 0.05）.Data which had analyzed by two-way ANOVA indicated that lesion of ACC caused significant decrease in kaolin consumption post-rotation（P〈0.05）with comparison of control group.Conclusion：Taken together with the histological results indicating that the electrolysis was restricted to ACC,the present data suggest that ACC,through vestibular information processing by its neurons,exerts a facilitatory role in development of MS.