中文摘要：

生物体衰老是一个非常复杂的过程。研究发现核转录因子（NF-κB）在细胞衰老中具有重要作用，对于细胞衰老的研究具有重要意义。本文综述了近几年来NF-κB与细胞衰老的相关研究，包括NF-κB作用机制、衰老相关信号通路与NF-κB的串流（crosstalk），深入探讨NF-κB与衰老的关系可为阐明衰老的分子机制及延缓衰老提供新的思路。

英文摘要：

Organism senescence is a very complicated process. The recent studies have found that the nuclear transcription factors-κB （NF-κB） plays an important role in the cell senescence and it has the vital significance on the study of cell senescence. The related research of NF-κB and cell senescence in recent years is reviewed in this paper. The main contents include NF-κB mechanism, the crosstalk of NF-κB and aging-related signaling pathways. Delving into the relationship between NF-κB and cell senescence can help to elucidate the molecular mechanism of aging and provide new idea for anti-aging.