中文摘要：

在 1985 从中国的湖北省孤立的鸟的流行性感冒病毒(A/duck/Hubei/216/1985/H7N8 ) 的分子、病原的性质被描绘。红血球凝聚素基因(哈) 有的 Dk/Hb/216/85/H7N8 多重氨基酸序列(在在 HA1 和 HA2 之间的连接的肽的 -PEIPKGRG-) ，它被认为是区分分子低致病力特征。在 Dk/Hb/216/85/H7N8 的基因(M， NP， NS， PA 和 PB2 ) 之中的主人标记的关键地点类似于 H5N1 病毒的那些。种系发生的分析证明 Dk/Hb/216/85/H7N8 的基因(M， NS 和 PB2 ) Gs/Guangdong/1996/H5N1 (Gs/GD/96 ) 与那些仔细聚类，暗示 Gs/GD/96-like 病毒的三古老的基因在在 1980 年代期间的华中一直在传播。在试验性的感染， Dk/Hb/216/85/H7N8 是低层的对鸡和老鼠病原，与分子的特征一致哈基因。

英文摘要：

The molecular and pathogenic properties of avian influenza virus （A/duck/Hubei/216/1985/H7N8） isolated from Hubei Province of China in 1985 were characterized. The hemagglutinin gene （HA） of Dk/Hb/216/85/H7N8 had the multiple amino acid sequences （-PEIPKGRG-） at the connecting peptide between HA1 and HA2, which is considered to be a distinguishing molecular characteristic of low pathogenicity. The key sites of host markers among the genes （M, NP, NS, PA and PB2） of Dk/Hb/ 216/85/H7N8 were similar to those of H5N1 viruses. Phylogenetic analysis showed that the genes （M, NS and PB2） of Dk/Hb/216/85/H7N8 clustered closely with those of Gs/Guangdong/1996/H5N1 （Gs/GD/96）, implying that three ancient genes of Gs/ GD/96-like viruses had been circulating in Central China during the 1980s. In experimental infection, Dk/Hb/216/85/H7N8 was lowly pathogenic to chickens and mice, consistent with the molecular feature of HA gene.