中药配伍是中医用药的主要形式,也是中药有别于化学药的重要特点。芳香开窍类中药如冰片、石菖蒲、麝香等具有"芳香开窍,引药上行"的功效,在复方中常被用作"使药"。开窍中药在复方中不仅可促进一些难吸收成分的胃肠吸收,同时可通过开放血脑屏障促使配伍成分进入中枢神经系统。深入了解芳香开窍类中药促吸收机制,可为中药复方临床用药的科学性提供依据。本文对芳香开窍类中药作为"使药"促进胃肠道吸收、脑部吸收以及其作用机制等方面进行综述。
Compatibility of traditional Chinese medicine (TCM) as the primary form of Chinese medicine plays an important characteris- tic which is different from the chemical medicine. Aromatic refreshing TCM has been usually used as "adjuvant drug" in the compound with its effects of inducing resuscitation and promoting other drugs entering into the brain, such as borneol, Acorns tatarinowii Schott and musk. Aromatic refreshing TCM not only can promote the gastrointestinal absorption of some difficult absorption component, also can make it into the central nervous system (CNS) by opening the blood -brain barrier (BBB). Further exploration of action mecha- nism of aromatic refreshing TCM, can provide reference for clinical rational administration. The aim of this review is to summarise? the knowledge of Aromatic refreshing TCM acting as "adjuvant drug" promoting the gastrointestinal absorption, the brain uptakes and its mechanism of action.