中文摘要：

目的本研究提出基于磁共振弥散张量成像（DiffusionTensorImaging，DTI）图像的脑干肿瘤术前路径自动规划设计，对重要组织结构的有效规避和减少手术致残率具有重要意义。方法本研究将DTI功能像与核磁共振结构像相结合，进行脑干肿瘤术前路径自动规划。首先对DTI图像进行变形矫正，将DTI功能像与核磁共振结构像进行配准，然后提取两种图像的关键区域信息，利用引力斥力模型通过样条曲线插值对术前信息进行路径自动规划设计。结果该方法提取术前的纤维束与组织结构信息，完成术前自动路径规划，直观的实现了对关键组织最大化规避的路径规划设计。结论该方法通过对术前DTI图像的矫正配准以及区域纤维束的追踪提取，为医生在术中规避重要组织区域提供直观信息。

英文摘要：

Objective We proposed an automatic preoperative path planning method based on diffusion tensor imaging(DTI)for brain stem tumor surgery to effectively circumvent the important organizations and reduce the disability rate.Methods In this paper,DTI and magnetic resonance imaging(MRI)were combined effectively for the automatic preoperative path planning of brain stem tumor surgery.Firstly,DTI was corrected and registered with MRI.Then,the key region information of these two modal images was extracted for automatically designing the surgical path with gravity repulsion model and spline interpolation.Results Our method could complete automatic preoperative path planning through extracting the information of preoperative fiber bundle and tissue structure.In additional,it could realize the path planning intuitively and maximize avoid important tissue damage.Conclusion The proposed automatic preoperative path planning method based on the preoperative DTI can provide intuitive information for the doctors to avoid important tissue damage.