中文摘要：

使解调的一种非线性的成像技术超声对比代理人(UCA ) 的反应的第二个泛音部件被建议。UCA 灌注成像方法分别地从三个方面，数学原则，模拟和超声实验被调查了。调制频率(FM ) 信号刺激被介绍了第一在医药超声成像增加 Signal-to-Noise 比率(SNR ) 。如果，理论模拟和一个超声实验被执行调查 cosineenveloped 调制频率的信号刺激能在 UCA 成像被使用增加 SNR 和 Contrast-to-Tissue 比率(CTR ) 。为了获得好成像，合适的参数和权利，播送信号上的信封被需要，并且差距也在播送信号带宽和译码的匹配过滤器带宽之间被需要。一幅泛音图象与编码刺激和译码的过滤器使用被获得。结果建议用这个泛音成像方法，图象能与好 SNR 和 CTR 被得到。同时，听觉的结果被适合于理论结果很好。

英文摘要：

A nonlinear imaging technique that demodulated the second harmonic component of the response of the Ultrasound Contrast Agent （UCA） was proposed. The UCA perfusion imaging method has been investigated from three aspects, mathematics principle, simulation and ultrasound experiment, respectively. Frequency-Modulated （FM） signal excitation has been introduced to increase Signal-to-Noise Ratio （SNR） in medical ultrasound imaging firstly. A theoretical simulation and an ultrasound experiment were performed to investigate if a cosine- enveloped frequency-modulated signal excitation could be applied in UCA imaging to increase SNR and Contrast-to-Tissue Ratio （CTR）. To obtain a good imaging, suitable parameters and a right envelope on the transmitted signal were needed, and a gap was also needed between the transmitted signal bandwidth and the decoded match filter bandwidth. A harmonic image was obtained with using of coded excitation and the decoded filter. The results suggested that using this harmonic imaging method, image could be got with good SNR and CTR. At the same time, the acoustical results were agreed with the theoretical results well.