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艾灸对急性胃溃疡大鼠胃黏膜组织形态学和血流量的影响
  • ISSN号:1673-1727
  • 期刊名称:《中华中医药杂志》
  • 时间:0
  • 分类:R573[医药卫生—消化系统;医药卫生—临床医学;医药卫生—内科学]
  • 作者机构:[1]厦门大学医学院,厦门361005, [2]江西中医药大学,南昌330004, [3]深圳市福田区中医院,深圳518000
  • 相关基金:国家自然科学基金项目(No.30960484,No.81260556)~~
中文摘要:

目的:研究艾灸对急性胃溃疡大鼠胃黏膜组织形态的变化和血流量的影响,探讨艾灸促进胃黏膜损伤修复的生物学机制。方法:将大鼠随机分为正常组、模型组、胃经穴组和对照点组,采用束缚冷应激法制作急性胃溃疡大鼠模型,光镜下观察大鼠胃黏膜溃疡指数,多导生理记录仪检测大鼠胃黏膜血流量。结果:与模型组比较,胃经穴组大鼠的胃黏膜溃疡指数值均降低,胃黏膜形态学明显改善,胃黏膜血流量显著增加(P〈0.01);与对照点组比较,胃经穴组大鼠胃黏膜溃疡指数、形态学和血流量改善更为明显(P〈0.01)。结论:艾灸可增加胃黏膜血流量,促进胃黏膜的损伤修复,并且存在一定的经脉脏腑相关性。

英文摘要:

Objective: To study the biological repair mechanisms of gastric mucosa damage, through the effect of morphology and blood flow volume of gastric mucosa in rats with acute gastric ulcer treated by moxibustion. Methods: rats were randomly divided into normal group, model group, stomach meridian group, control point group. Except for the normal group, all the rats were established into the gastric mucosa injury model by cold restrain stress. Gastric mucosal injury index in rats were observed by light microscopy, the gastric mucosal blood flow volume in rats were tested by the physiological recorder detection. Results: Compared with the model group, the gastric mucosa ulcer index was decreased, the gastric mucosa morphology was significantly improved, gastric mucosal blood flow volume was significantly increased in stomach meridian group (P〈0.01). The gastric mucosa ulcer index, gastric mucosa morphology and blood flow volume in stomach meridian group were improved significantly than those in control point group (P〈0.01). Conclusion: Moxibustion on the stomach meridian could increase the gastric mucosai blood flow volume, promote the repair of gastric mucosa injury, and there is a certain correlation between meridians and viscera.

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期刊信息
  • 《中华中医药杂志》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中国中医药学会
  • 主编:佘倩
  • 地址:北京市和平街北口樱花路甲4号
  • 邮编:100029
  • 邮箱:
  • 电话:
  • 国际标准刊号:ISSN:1673-1727
  • 国内统一刊号:ISSN:11-5334/R
  • 邮发代号:18-90
  • 获奖情况:
  • 国家中医药管理局优秀期刊一等奖
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,美国剑桥科学文摘,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:36061