中文摘要：

肺纤维化是由各种损害引起组织内细胞外基质异常增生和过度沉积的一种病理过程,并最终破坏正常组织结构和功能。肺纤维化是导致众多疾病的重要原因,对人体健康危害极大。因此,进一步阐明肺纤维化发病机制,将有助于了解疾病的发生发展和防治。本文将就近年关于纤维化发病机制的研究进展作简要概述并展望未来研究工作。

英文摘要：

Pulmonary fibrosis is a pathological process of tissue extracellular matrix abnormal hyperplasia and excessive accumulation caused by a variety of damages, which ultimately leads to the destruction of normal tissue structure and function.Pulmonary fibrosis is an important cause for many diseases, and is greatly harmful to human health.Therefore, to further clarify the pathogenesis of pulmonary fibrosis can help to understand the development and prevention of the disease.The paper briefly summarizes the research progress of pathogenesis of pulmonary fibrosis in recent years and look forward to the prospect of future research.