如今纳米生物技术的研究正以迅猛的势头不断发展。量子点作为一种新型的纳米荧光探针,由于其优越的光电学特性在生物学和毒理学领域有着广阔的应用前景。神经毒理学作为毒理学的一个重要分支,量子点的应用也给该领域带来了技术上的革命。本文重点阐述了量子点作为一种新型单分子技术和一种优秀的荧光探针在神经毒理学研究中的应用。同时,作者还简要介绍了量子点进入机体神经系统的途径和影响其应用的一些因素,为今后量子点的生物安全性研究和更好地应用提供了有价值的参考。
With the rapid development of nanotechnology, quantum dots (QDs), as a new type of nano-fluorescence probes, have been widely used in biology and toxicology due to their unique photoelectric properties. Moreover, QDs have introduced a technological innovation in the field of neurotoxicology, which as an important branch of toxicology. The primary focus of this review is the application of QDs in neurotoxicological studies as a novel sin- gle molecular technology and an excellent fluorescent probe. The routes of QDs entering into the nervous system and potential factors that could impact QDs' applications were also briefly introduced here in order to guide further related researches on the biosafety and better applications of QDs.