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中文摘要：
目的：探讨海洛因成瘾者脑白质的损害情况。方法：用弥散张量成像技术检测15位海洛因成瘾者的脑白质情况,并与16位正常对照者进行比较。结果：发现与正常对照者相比,海洛因成瘾者在多处脑区的脑白质出现各向异性分数（FA）的明显下降（P〈0.001）,主要包括额叶、顶叶、岛叶和胼胝体。结论：海洛因成瘾者存在脑白质微结构的损害。
英文摘要：
Objective To examine white matter integrity in heroin-dependent patients and matched normal controls with diffusion tensor imaging （DTI）.Methods The fractional anisotropy was compared between 15 heroin-dependent patients and 15 controls.Results We found the fractional anisotropy was significantly decreased in specific brain regions of the heroin-dependent patients （P〈0.001 uncorrected）,including the frontal gyrus,the parietal lobule,the insula,and the corpus callosum.Conclusion The presence of microstructural abnormality is found in the white matter of several brain regions of heroin-dependent patients.
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