中文摘要：

中药炮制是中医药的特色和优势,也是最具我国自主知识产权的学科之一。中药炮制研究是连接中医学和中药学的桥梁,也是制约中药现代化的关键节点。目前大部分中药的炮制机制尚不明确,有待进行系统深入的研究。地黄炮制前后药性发生显著变化,临床应用也各不相同,其炮制过程中发生了复杂的化学变化。近年来,国内外专家对地黄炮制过程化学成分变化及其机制进行了深入研究,取得了系列研究成果,这些研究思路和方法为中药炮制研究提供了借鉴,也为中药炮制研究提供了重要示范。

英文摘要：

Chinese materia medica （CMM） processing is one of the characteristics and advantages of traditional Chinese medicine （TCM）, which is also an important discipline with our independent intellectual property rights. The mechanism of CMM processing is the key point of CMM research, which is also the key node of CMM modernization. Most mechanisms of CMM processing are unclear until now, which request the systematical and deep research. Raw and processed Rehmanniae Radix have the different pharmacological effects in clinical application, because there are lots of chemical reactions occurred during the steaming process. In the recent years, scientists all over the world have done lots of research on the changes and mechanisms of Rehmanniae Radix by steaming process under high temperature, and series of research achievements were obtained with the application of many new methods and technologies. These achievements provide not only many new ideas and methods for the mechanism exploration of CMM t~rocessin~, but also the demonstratinn f,~r ~,~ h; ~ _, _ ~