中文摘要：

人类胃肠道内栖居着数量众多且种类繁杂的微生物群，肠道菌群稳态的维持对于宿主正常代谢活动的有序进行至关重要。随着人体微生物组研究的开展，肠道菌群变化对骨代谢活动的影响引起众多学者的关注。本文对肠道微生物与骨健康的关系、肠道微生物影响骨代谢的潜在机制以及肠道微生物对牙槽骨可能发挥的调控作用进行综述，以期为肠道微生物与骨代谢相关疾病的病因学研究以及疾病诊疗提供新的思路。

英文摘要：

Heterogeneous microbiota dwells in the human gastrointestinal tract, and the maintenance of gut microbiota homeostasis plays an important role in normal host metabolism. With advancement in studies on human microbial communities, the effects of gut microbiota on bone metabolism have been extensively investigated. This review summarizes the research progress on the association between gut microbiome and bone metabolism and focuses on the relationship between gut microbiota and bone fitness, the potential mechanisms of mutual interactions, and the relationship between intestinal microbiota and alveolar bones. Research advancement in this field not only enhances our understanding of the etiological role of gut microbiota in bone metabolism-related diseases but also possibly provides a novel approach for the management of bone diseases involving the microbiota.