通过纳米碘化亚铜催化苯酚与硝基芳烃交叉偶联,发展了一种合成二芳基醚的有效方法.该反应具有原料易得、官能团兼容性强、反应迅速、产率高等优点.催化剂在循环使用三次后,催化活性未显著降低.此外,该反应对空气和水分不敏感.
A general and efficient method for the synthesis of diaryl ethers via nano-Cu I catalyzed coupling reaction of phenols with nitroarenes was developed. The efficiency of this reaction was demonstrated by its compatibility with a range of functional groups in good to excellent yields. The catalyst could be recycled for three times without significant loss of the catalytic activity.