中文摘要：

目的对远志去心（根皮）与不去心（根）的药材进行比较，为远志科学炮制加工方法的制定提供参考。方法通过化学成分分析和药效学研究相结合方法，对远志根皮、根和木心进行全面、系统比较，即采用多指标定量结合指纹图谱分析方法对远志根皮、根及木心的化学成分进行定性、定量分析；采用镇静安神、止咳祛痰等远志传统的药效学指标进行根皮与根的药效学评价。结果根、根皮和木心所含化学成分类似，但各有效成分的含量以根皮〉根〉木心。药效学研究结果表明，远志根皮和根的药效没有明显差异，但远志根在止咳、祛痰方面表现了更好的作用趋势。结论为避免资源的浪费及去心过程带来的人力、物力损耗，建议远志没有必要去心。

英文摘要：

OBJECTIVE To carry out a comparison between the cortexes and the roots of Polygala tenuifolia, and to supply references for developing scientific processing method of P. tenuifolia. METHODS A comprehensive comparison was made by comparing the chemical constitution and pharmacological activities of the cortexes and the roots of P. tenuifolia, i. e. , multi-components determination and fingerprint analysis were used to analyze their chemical constituents, and the traditional pharmacological actions of P. tenuifolia, such as cough-relieving, sputum-removing and sedative effects were used to evaluate their efficacy. RESULTS The chemical constitution of the cortexes, roots and heartwoods of P. tenuifolia was similar, but the contents of the various effective components in the cortexes were more than those in the roots and heartwoods. The pharmacological results revealed that there was no obvious difference between the cortexes and the roots of P. tenuifolia for their activities of cough-relieving, sputum-removing and sedative actions. The roots of P. tenuifolia showed a better tendency than the cortexes for cough-relieving and sputum-removing activities. CONCLUSION In order to avoid the waste of crude drugs, and to save the cost during heartwood-discarding, the heartwoods of P. tenuifolia are suggested to be kept.