中文摘要：

目的：建立舒胸口腔崩解片中三七皂苷R1、人参皂苷Rg1、人参皂苷Rb1的含量测定方法。方法：采用高效液相色谱法,Kromasil-C18色谱柱（4.6mm×250mm,5μm）,以乙腈-水为流动相进行梯度洗脱,流速1.0mL·min^-1,柱温30℃,检测波长203nm。结果：三七皂苷R1、人参皂苷Rg1和Rb1的线性范围分别为0.41~4.08μg（r=0.9997）、0.80~8.04μg（r=0.9993）、0.82~8.20μg（r=0.9994）。该方法平均回收率三七皂苷R1为98.97%（RSD=2.25%,n=6）、人参皂苷Rg1为101.98%（RSD=2.55%,n=6）、人参皂苷Rb1为98.71%（RSD=2.91%,n=6）。结论：该法简便、准确、重现性好,可用于舒胸口腔崩解片中3种皂苷的含量测定。

英文摘要：

Objective：To establish a method for determining the content of Notoginsenoside R1 and Ginsenoside Rg1,Rb1 in the Shuxiong Orally Disintegrating Tablets.Methods：The product was analyzed by HPLC.The Kromasil-C18column（4.6mm×250mm,5μm）was used with a mobile phase of acetonitrile-water gradient elution,the flow rate was 1.0mL·min-1,203 nm as the decetion wavelength and column temperature was 30℃.Results：The linear rang of R1,Rg1,Rb1 was 0.41~4.08μg（r=0.9997）,0.80~8.04μg（r=0.9993）,0.82~8.20μg（r=0.9994）.The average recovery was 98.97%（RSD=2.25%,n=6）,101.98%（RSD=2.55%,n=6）,98.71%（RSD=2.91%,n=6）.Conclusion：The method is simple,accurate,and sensitive,and can be used for controlling the quality of Shuxiong Orally Disintegrating Tablets.