中文摘要：

以乙酰乙酸乙酯为原料,经缩合、氧化、还原和氯代等反应合成了3-甲基-5-碘甲基-1H-吡咯-2,4-二（甲酸乙酯）（5）;5分别与乌洛托品,吡啶和三甲胺经取代反应合成了3个吡咯季铵盐6a-6c,其中5和6a-6c均为新化合物,其结构经^1H NMR,IR和ESI-MS表征。

英文摘要：

An intermediate,diethyl 5-（ iodomethyl）-3-methyl-1H-pyrrole-2,4-dicarboxylate（ 5）,was prepared by the reaction of condensation,oxidation,reduction and chlorination from ethyl acetoacetate. Three pyrrole quaternary ammonium salts（ 6a - 6c） was synthesized by substitution reaction of 5with urotropin,pyridine and trimethylamine,respectively. 5 and 6a - 6c were novel compunds. The structures were characterized by^1 H NMR,IR and ESI-MS.