中文摘要：

目的：研究分析传统开颅与钻孔引流联合尿激酶溶解术治疗中年高血压性脑出血患者颅内压的临床疗效。方法：选取2013年4月至2014年10月我院接收的的150例高血压性脑出血患者,根据治疗方式进行分组,对照组患者实行传统开颅手术,试验组患者实行钻孔引流联合尿激酶溶解术,比较两组患者的颅内压变化情况、近期临床疗效和远期生存质量。结果：试验组患者在术后72h的颅内压（548.93±184.93）mm H2O显著高于对照组患者早术后72h的颅内压（396.67±133.89）mm H2O;试验组术后1周评分（24.92±8.82）分显著对照组术后1周评分（28.27±9.86）分;试验组远期生存质量良好90.67%显著高于对照组生存质量良好57.33%,差异有统计学意义（P〉0.05）。结论：钻孔引流联合尿激酶溶解术治疗高血压性脑出血对颅内压的影响大于传统开颅治疗,但其近期临床疗效和远期生存质量具有显著临床优势,在临床具有重要应用价值。

英文摘要：

Objective： To study the clinical efficiency of traditional craniotomy and puncture drainage combined urokinase clot lysis effect on intracranial pressure of elderly patients with primary hypertension cerebral hemorrhage. Method： Selected 150 primary hypertension cerebral hemorrhage from Apr. 2013 to Oct.2014 in our hospital,assigned them according to the way of treatment,patients in control group used traditional craniotomy,patients in experimental group used puncture drainage combined urokinase clot lysis,compared their intracranial pressure changes,short-term clinical effects and long term survival quality. Result： Intracranial of postoperative 72 h pressure of the experimental group（ 548.93 ＋ 184.93） of mm H2 O was significantly higher（ 396.67 ＋ 133.89） mm H2 O of control group; the experimental group score（ 24.92 ＋ 8.82） after 1 week of operation was significantly lower than（ 28.27 ＋ 9.86） points of control group; quality of life of experiment group 90.67% was significantly better than 57.33% of control group,the difference had statistically significant（ P〈0.05）. Conclusion： The effect of trepanation and drainage of intracranial pressure is better than the traditional craniotomy treatment combined with urokinase clot lysis in the treatment of hypertensive cerebral hemorrhage,but the clinical effect in the near future and long term survival quality has a significant clinical advantage and has important value.