中文摘要：

我们调查了兔子的能力出血性的疾病病毒(RHDV ) 衣壳蛋白质(VP60 ) 到与次要的结构的蛋白质 VP10 明确地交往，用一在里面 vivo 基于房间的将哺乳动物的二混血儿的系统。RHDV VP60 蛋白质与 VP10 明确地交往了。有特定的抗体的 Immunofluorescence 分析和 co-immunoprecipitation 揭示了生物学上重要的 VP60/VP10 建筑群的存在。然而，当 VP60 被划分成二碎片时，在 VP60 和 VP10 之间的相互作用戏剧性地被损害。这些结果将对进一步调查 RHDV 粒子汇编的机制有用。

英文摘要：

We investigated the ability of the rabbit hemorrhagic disease virus （RHDV） capsid protein （VP60） to interact specifically with the minor structural protein VP10, using an in vivo cell-based CheckMateTM Mammalian Two-Hybrid System. RHDV VP60 protein interacted specifically with VP10. Immunofluorescence analysis and co-immunoprecipitation with specific antibodies revealed the existence of biologically important VP60/VP10 complexes. However, when VP60 was divided into two fragments, the interaction between VP60 and VP10 was impaired dramatically. These results will be helpful for further investigating the mechanism of RHDV particle assembly.