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新型吡啶酮类HIV-1双靶点(RT/IN)抑制剂的设计、合成及生物活性评估
  • ISSN号:1003-1057
  • 期刊名称:《中国药学:英文版》
  • 时间:0
  • 分类:S852[农业科学—基础兽医学;农业科学—兽医学;农业科学—畜牧兽医] Q78[生物学—分子生物学]
  • 作者机构:[1]State Key Laboratory for Infection Disease Prevention and Control, National Center for AIDS/STD Control and Prevention (NCAIDS), Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseas, Chinese Center for Disease Control and Prevention (China-CDC), Beijing 102206, China
  • 相关基金:This work was supported by grants from State Key Laboratory for Infectious Disease Prevention and Control (2011SKLID102), National Nature Science Foundation of China (81172733).
中文摘要:

<正>The success of combined antiretroviral therapy(cART)has dramatically improved the clinical outcomes of HIV infection and made HIV infection a chronic disease.Nonetheless,cART alone cannot eliminate viral reservoirs and fully recover patients’health,so the patients have to receive this treatment for lifetime.Therefore,researchers have focused their efforts on the cure for HIV infection.In

英文摘要:

The success of combined antiretroviral therapy (cART) has dramatically improved the clinical outcomes of HIV infection and made HIV infection a chronic disease. Nonetheless, cART alone cannot eliminate viral reservoirs and fully recover patients' health, so the patients have to receive this treatment for lifetime. Therefore, researchers have focused their efforts on the cure for HIV infection. In recent years, some intriguing and inspiring cases indicated that the cure of HIV infection (HIV cure) or durable alleviation of HIV infection may not be a dream any more. 'Berlin Patient' 'Mississippi Baby', and probably 'Long Beach Baby' have brought great hope to the HIV cure. Many scientists believe that the HIV cure is just a question of time.

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期刊信息
  • 《中国药学:英文版》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:北京大学药学院
  • 主编:王夔
  • 地址:北京市学院路38号
  • 邮编:100083
  • 邮箱:zggy@mail.bjmu.edu.cn
  • 电话:010-82801713
  • 国际标准刊号:ISSN:1003-1057
  • 国内统一刊号:ISSN:11-2863/R
  • 邮发代号:
  • 获奖情况:
  • 国内外数据库收录:
  • 被引量:708