中文摘要：

中药不良反应事件在国际上的出现,中药安全性问题逐渐受到重视。除经典的毒理学评价外,近年来在中药安全性研究领域包括中药毒性研究方面也涌现出了许多新的思路和方法,有效拓展了中药毒性研究的深度和广度,并从中发现了一些有价值的线索。对近年来关于中药毒性研究的相关思路和方法进行梳理分析和归纳总结,并结合相关工作,综述了中药毒性研究进展,提出加强中药毒性研究有重要意义,并有助于指导中药的安全合理应用。

英文摘要：

The safety issues of Chinese materia medica（CMM） have been gradually taken seriously along with the CMM side effects increasing in the worldwide use.Except the classic toxicology evaluation,more new ideas and methods were emerged in the field of safety evaluation including toxicity study on CMM,which effectively expands the depth and width of toxicity study on CMM and many valuable clues have been found.Recent advances in thoughts and methods of study on CMM toxicity are reviewed and summarized and the importance of the study in this field is highlighted,which may guide the safety use of CMM.