中文摘要：

目的 探讨儿童胼胝体压部病变的临床特征及预后.方法 回顾性分析2013年1-12月山西省儿童医院神经内科收治的胼胝体压部病变患者的临床特征及预后,分析该病可能的致病机制.结果 16例患者中,男性8例,女性8例;年龄1 ～13岁,平均（3.44±3.65）岁;病因分为病毒性脑炎、抽搐、轮状病毒感染等;出现的临床症状包括抽搐（10例）、消化道症状（8例）、发热（8例）、颈抵抗阳性（6例）、精神萎靡（5例）、意识改变（2例）、头痛及头晕（各1例）.随访到的胼胝体病变持续时间为13 ～50 d,平均（28.8±10.2）d.头颅核磁均提示胼胝体压部孤立的卵圆形病灶,T1加权像低或等信号,T2加权像、弥散加权成像高信号,表观扩散系数像为低信号.结论 儿童胼胝体压部病变病因较成人少,多为病毒性脑炎、抽搐、轮状病毒感染等所致,临床表现多为发热、消化道症状（呕吐、腹泻）、抽搐等.随访到的病例病灶和症状均为可逆性,而且预后良好.

英文摘要：

Objective To explore the prominent clinical features and the prognosis of corpus callosum solitary lesions cases in children.Methods There were 16 cases with corpus callosum solitary lesions receiving treatment at our hospital from January to December 2013.All of the clinical features were collected and retrospectively analyzed.Results The 16 cases aged 1 year to 13 years with an average age of （3.44 ± 3.65） years.The causes of the disease included the viral encephalitis,convulsions,and rotavirus infection.The most prevalent disorders were convulsions （10 cases）,gastrointestinal symptoms （8 cases）,fever （8 cases）,positive cervical resistance （6 cases）,fatigue （5 cases）,altered states of consciousness （2 cases）,headache （1 case）,and dizziness （1 case）.Corpus callosum lesions lasted for 13-50 days,with an average of （28.8 ± 10.2） days.Cranial magnetic resonance showed the splenium of the corpus callosum with isolated oval lesions,low signal on T1 weighted images and apparent diffusion coefficient images,high signal on T2 weighted images and diffusion weighted images.Conclusions The splenium of the corpus callosum lesions of children occur in a lower rate than adults with the etiology including intracranial infection,convulsions and rotavirus infection.Main clinical manifestations include fever,convulsions and gastrointestinal symptoms （nausea,diarrhea,etc）.The cases followed-up showed the lesions and symptoms are reversible,and the prognosis is good.