妊娠妇女感染流感病毒的患病率增高,易继发严重的并发症。美国疾病预防控制中心推荐妊娠妇女感染甲型H1N1流感用奥司他韦治疗。本文对临床前和临床研究数据评价妊娠期服用奥司他韦的安全性进行分析,并简述甲型H1N1流感产生不利的妊娠和胎儿状况。
Pregnant women with influenza virus are at increased risk of severe complications and morbidity.Oseltamivir has been recommended for the treatment of pregnant women with influenza A H 1 N1 virus by the Centers for Disease Control and Prevention ( CDC ) of American.This paper analysed pre -clinical and clinical data to assess the safety of osel-tamivir used during pregnancy , and reviewed the poor outcomes of preg-nant and fetus when pregnant women infected with influenza A H 1 N1 virus.