中文摘要：

采用二维红外相关技术，对黄芩原药材、饮片及其提取物进行分析研究。在一维红外光谱中，各样本间的谱图十分相似，导数光谱分析发现，经过炮制之后在1 745和1 411 cm^-1处吸收峰向高波数位移，1 357 cm^-1处吸收峰向低波数位移。二维红外谱图显示的药效组分特征差异明显，生黄芩在1 300～1 800 cm^-1波数范围内有4个特征峰，以1 575 cm^-1最强;黄芩片的自动峰有3个区域;酒黄芩的自动峰有2个区域。各区域内自动峰均为正相关。不同样品总苷提取物的一维谱图显示, 在1 615, 1 585, 1 450 cm^-1（苯环骨架振动）和1 658 cm^-1（CO）附近均有特征吸收，二阶导数谱图给出在1 656 cm^-1（黄酮的CO）附近有特征峰，推测共有的成分为酚苷类化合物。二维谱图在800～1 800 cm^-1波段均体现苯环骨架振动的5个自动峰1 366，1 420，1 508，1 585，1 669 cm^-1。可见红外光谱宏观指纹技术可提供大量整体信息，能够较准地把握黄芩的整体质量。可用于研究黄芩药材及饮片特征的相关性。

英文摘要：

2D-IR correlation spectroscopy was used to do the research on crude and prepared drug of radix scutellariae and the extracts of them. The results show that the holistic shape of peaks among them are similar in the FTIR spectra. In second derivative spectra, the two absorption peaks： 1 745 and 1 411 cm^-1 of processed products move to the bigger wavenumber direction, while 1 357 cm ^-1 of processed products moves to the smaller wavenumher direction） There are conspicuous differences in Twodimensional infrared correlation spectroscopy among them： Four characteristic peaks are shown between 1 300 and 1800 cm^-1. The intensity of peak at 1 575 cm ^-1 is the strongest. There are three main districts about the autopeaks of sliced seutellariae.Wine-fried scutellariae has two auto-peak districts, in which all the auto-peaks are positively correlated. The FTIR spectra of to tal glycoside extract of different samples present characteristic peaks at 1 615, 1 585, 1 450 cm 1 （vibration of phenyl framework） and 1 658 cm^-1 （ =C-O ）respectively, therefore, the authors speculated that their mutual component is the compound of phenolic glycoside. The two-dimensional infrared correlation spectra present five automatic peaks （vibration of phenyl frame work） in 800-1 800 cm^-1 （1 366, 1 420, 1 508, 1 585, 1 669 cm ^-1 ）. So the authors can conclude that a lot of information can be provided by macro-fingerprint technology of infrared spectroscopy which can evaluate overall quality of radix scutellariae accurately and be used to study the characteristics of relevance of crude and prepared scutellariae.