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身心乐静法对应激反应后机体心率、唾液皮质醇的调节效应
  • 期刊名称:中国临床康复
  • 时间:0
  • 页码:184-187
  • 语言:中文
  • 分类:R493.25[医药卫生—康复医学;医药卫生—临床医学]
  • 作者机构:[1]大连理工大学神经信息学研究所身心调节实验室,辽宁省大连市116023, [2]中国科学院脑与认知科学国家重点实验室,北京市100101, [3]大连医科大学附属第一医院核医学放免室,辽宁省大连市116001
  • 相关基金:国家自然科学基金资助(60472017,30670699);教育部重大项目(KP0302)
  • 相关项目:用动态因果模型研究汉字字形加工的脑内规律
中文摘要:

目的:观察身心乐静法对应激反应后机体心率、唾液皮质醇浓度的调节作用。 方法:观察于2006-05/06在大连理工大学神经信息学研究所身心调节实验室完成。选择33名大连理工大学物理系三年级学生,男22名,女11名,年龄19~21岁,身体健康,均知情同意。按随机数字表法分为2组,身心乐静法调节组16名,对照组17名。①身心乐静法调节组在做应激测试前接受5d调节法训练,采用身心乐静法,在背景音乐下跟随指导语作调节;对照组同期5d内未经过任何调节放松训练。②所有被试到实验室后休息5min,测基线值的心率,采集唾液标本。采用心算作为实验室急性应激源,给被试做数字连减测试3min,立即测应激后的心率,采集唾液标本。然后身心乐静法调节组作20min身心乐静法调节,对照组静坐20min,测调节/静坐20min后的心率,采集唾液标本。采用放射免疫分析方法测定唾液皮质醇浓度。 结果:33名学生全部完成实验,均进入结果分析,无脱落。①两组被试基线和应激后的心率和唾液皮质醇浓度比较:两组被试应激后的心率和唾液皮质醇浓度均显著高于基线值[身心乐静法调节组:(87.71±13.77,71.50±10.28)次/min,(10.13±3.64,7.90±3.51)nmol/L;对照组:(84.12±14.30,77.65±9.14)次/min,(13.79±6.18,10.03±4.01)nmol/L(P〈0.01)],产生有效的急性应激状态。②两组被试调节/静坐20min后的心率和唾液皮质醇浓度比较:两组被试调节/静坐20min后的心率已下降到基线水平,差异无显著性意义(P〉0.05)。身心乐静法调节组应激后调节20min唾液皮质醇浓度显著低于对照组[(12.95±4.26,17.58±7.48)nmol/L(t=2.130,P〈0.05)]。 结论:身心乐静法能有效地抑制体内唾液皮质醇的过多分泌,调节机体的应激状态,?

英文摘要:

AIM: To observe the effect of Hi-method for body and mind regulation on heart rate and salivary cortisol level response to stress reaction. METHODS: The experiment was carried out in the Institute of Neuroinformatics, Laboratory of Body and Mind, Dalian University of Technology between May and June in 2006. Thirty-three healthy subjects (the 3^rd-year Physics students of Dalian University of Technology, 22 males and 11 females, aging 19-21 years) volunteered for the study with their informed consents, and were randomly divided into two groups. ① Himethod treatment group (n=16) attended training for 5 days before stress test. Subjects practiced Hi-method while listening to the instruction and background music. The control group (n=17) did not receive any relax training during that period. ② All subjects were given a 5-minute rest at the laboratory. We adapted the mental arithmetic task as the psychological acute laboratory stressor. Subjects were instructed to undergo a 3-minute serial subtraction task, afterwards the treatment group performed 20-minute Hi-method, whereas the control group quietly sat for 20 minutes. We repeatedly recorded the heart rate and collected saliva samples on the time points of baseline, right after stress task and 20 minutes after stress task. The salivary cortisol level was analyzed by radioimmunoassay. RESULTS: All 33 students finished the experiments and entered the result analysis without any dropout. ① The serial subtraction task successfully induced acute stress, the heart rate and salivary cortisol level significantly increased in the stress condition than at the baseline [Hi-method treatment group: (87.71±13.77, 71.50±10.28) beats/mira, (10.13±3.64, 7.90±3.51) nmol/L; Control group: (84.12±14.30, 77.65±9.14) beats/min, (13.79±6.18, 10.03±4.01) nmol/L, P 〈 0.01]. ② The heart rate on the time point of 20 minutes after stress task had no significant difference between two groups, beth dropping to the level of baseline (P

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