中文摘要：

缺血性脑卒中是老年人常见疾病，该疾病的高发病率、高死亡率以及高致残率特点使其成为全球关注的健康难题。JAK／STAT途径作为一条新近发现的信号转导通路，广泛参与神经元生长、分化、凋亡等过程，并且与脑卒中的病理生理过程密切相关，但目前对该通道在缺血性脑卒中疾病中的功能和作用机制尚未能完全阐明。该文将结合国内外JAK／STAT通路与缺血性脑卒中疾病的最新研究报道，对JAK／STAT信号转导途径在缺血脑卒中疾病过程中的作用和机制进行综述，并系统绘制缺血性脑卒中神经病变过程各种相关信号分子的网络关系图，以便更深入了解脑卒中病理发生过程，为寻找抗脑缺血疾病治疗新药，提供较为系统的科学文献支持。

英文摘要：

Ischemic stroke, gravely affecting human health with its increasing incidence rate , is a common disease of old age . JAK/STAT way , a recently discovered signaling pathway , is not only widely involved in processes of cell growth ,differentiation, and apoptosis ,but also closely related to the pathophysiology of stroke.However,the pathway function and mechanism in ische-mic cerebral stroke has not yet been fully elucidated .We will review the role and mechanism of JAK/STAT signal transduction pathway in ischemic stroke ,and scientifically draw network chart＆nbsp;between various related signal molecules in the process of ische-mic stroke neuropathy combining both domestic and foreign re-search reported in this paper , in order to better understand the pathological mechanism process of brain stroke , find new drugs for the treatment of cerebral ischemic diseases ,then provide more systematic scientific literature support .