中文摘要：

以20个发明问题和10个一般问题为实验材料,采用＂先问题-后原型＂的实验范式及基于体素的形态学分析技术（VBM）,探讨发明问题解决中的蔡格尼克效应.实验结果表明,发明问题解决能力与蔡格尼克效应呈显著正相关,即问题解决能力强的个体,回忆发明问题及未解决问题的能力也较强.进一步的实验表明,蔡格尼克效应与双侧的海马（hippocampal）、海马旁回（parahippocampal）的区域性灰质体积存在显著正相关性.这种关联可以从这些脑区对记忆、目标寻求、模糊容忍、情绪管理的作用上来理解.

英文摘要：

Zeigarnik effect means that participants tend to recall the unfinished/ unsolved tasks more frequently than the finished/solved ones during a subsequent memory task. To get a comprehensive understanding of the relationship between Zeigarnik effect and insightful problem solving,we need to adopt more research methods to explore the brain mechanisms of Zeigarnik effect. People typically go through a period of mental impasses and then are inspired by some heuristic knowledge in real-life scientific problem solving. For example,Newton obtained insights into the law of universal gravitation after observing a ripe apple dropping from the tree which he was sitting under. Based on this,Zhang Qinglin proposed that heuristic strategy is one of the usual strategies in problem solving. Based on the ＂prototype elicitation＂ theory,The present study selected 20 scientific inventions-creations problems as the material and adopted the ＂10 vs 10 learning and testing＂ as well as ＂testing-recalling＂ experimental paradigm. Besides,using voxel-based morphometry（VBM） and the score of ＂testing-recalling＂,we investigated the correlation between the zagarnik effect and regional grey matter volume（r GMV） in healthy subjects. The result showed that the Zeigarnik effect was to be positively correlated with r GMV in the bilateral Hippocampus and Parahippocampus. Based on these results above,we can speculated that bigger hippocampus and parahippocampal allow people to maintain target seeking as well as better tolerate ambiguity stimulation.