目的研究代谢综合征(MS)患者血脂与血清饱和脂肪酸的相关性。方法67例代谢综合征患者和60例正常对照者(NC)用酶法测定血脂,高效气相色谱法测定血清磷脂脂肪酸谱组分,并计算血清饱和脂肪酸(SFA)百分含量。结果MS组甘油三酯(TG)明显高于NC组[(2.6±1.3)mmol/LV8(1.5±0.4)mmol/L,P〈0.01]。MS组血清磷脂脂肪酸谱中总SFA百分含量较NC组显著升高[(45.7±2.5)%vs(42.1±2.0)%,P〈0.01],相关性分析显示TG浓度水平与总SFA百分含量正相关(r=0.35;P〈0.01)。结论MS患者SFA明显高于健康对照组,其血清TG水平与饱和脂肪酸正相关。
Objective To investigate the relationship between triglyceride (TG) and serum saturated fatty acid (SFA) in patients with metabolic syndrome (MS). Methods Sixty seven patients with MS and 60 normal control(NC) were enrolled into this study, the levels of TG was tested by enzymatic assay and fatty acid profile of phospholipids by capillary gas chromatography. The percent content of SFA was calculated. Results The level of triglyceride in MS group was higher than those in NC group [ (2.6 ± 1.3 ) mmol/L vs ( 1.5 ± 0.4) mmol/L,P 〈 0.01 ) ]. The levels of saturated fatty acid(SFA) in MS group were higher than those in NC group [ (45.7 ± 2.5 ) % vs (42.1 ± 2.0) %, P 〈 0.01 ) ]. The correlation analysis showed that the level of Tri- glyceride was positively correlated with percent content of SFA. Conclusion The level of serum phospholipid saturated fatty acid in MS group is higher than those in normal control group. The level of Triglyceride was positively correlated with SFA