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代谢综合征患者血清甘油三酯水平与饱和脂肪酸的相关性
  • ISSN号:1674-4152
  • 期刊名称:《中华全科医学》
  • 时间:0
  • 分类:R589[医药卫生—内分泌;医药卫生—临床医学;医药卫生—内科学]
  • 作者机构:[1]浙江省绍兴市人民医院内分泌代谢病科,312000, [2]浙江省绍兴市人民医院中心实验室,312000, [3]浙江大学食品科学与营养系,310029, [4]浙江大学城市学院医学与生命科学学院,310015
  • 相关基金:浙江省医药卫生基金重点项目(2008A156);浙江省绍兴市科技局资助项目(2008083);绍兴市科技局重点资助项目(2011A23022)
中文摘要:

目的研究代谢综合征(MS)患者血脂与血清饱和脂肪酸的相关性。方法67例代谢综合征患者和60例正常对照者(NC)用酶法测定血脂,高效气相色谱法测定血清磷脂脂肪酸谱组分,并计算血清饱和脂肪酸(SFA)百分含量。结果MS组甘油三酯(TG)明显高于NC组[(2.6±1.3)mmol/LV8(1.5±0.4)mmol/L,P〈0.01]。MS组血清磷脂脂肪酸谱中总SFA百分含量较NC组显著升高[(45.7±2.5)%vs(42.1±2.0)%,P〈0.01],相关性分析显示TG浓度水平与总SFA百分含量正相关(r=0.35;P〈0.01)。结论MS患者SFA明显高于健康对照组,其血清TG水平与饱和脂肪酸正相关。

英文摘要:

Objective To investigate the relationship between triglyceride (TG) and serum saturated fatty acid (SFA) in patients with metabolic syndrome (MS). Methods Sixty seven patients with MS and 60 normal control(NC) were enrolled into this study, the levels of TG was tested by enzymatic assay and fatty acid profile of phospholipids by capillary gas chromatography. The percent content of SFA was calculated. Results The level of triglyceride in MS group was higher than those in NC group [ (2.6 ± 1.3 ) mmol/L vs ( 1.5 ± 0.4) mmol/L,P 〈 0.01 ) ]. The levels of saturated fatty acid(SFA) in MS group were higher than those in NC group [ (45.7 ± 2.5 ) % vs (42.1 ± 2.0) %, P 〈 0.01 ) ]. The correlation analysis showed that the level of Tri- glyceride was positively correlated with percent content of SFA. Conclusion The level of serum phospholipid saturated fatty acid in MS group is higher than those in normal control group. The level of Triglyceride was positively correlated with SFA

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期刊信息
  • 《中华全科医学》
  • 中国科技核心期刊
  • 主管单位:国家卫生和计划生育委员会
  • 主办单位:中华预防医学会 安徽省微循环学会
  • 主编:
  • 地址:安徽省蚌埠市长淮路287号
  • 邮编:233004
  • 邮箱:zhqdyx@163.com
  • 电话:0552-3051890
  • 国际标准刊号:ISSN:1674-4152
  • 国内统一刊号:ISSN:11-5710/R
  • 邮发代号:26-200
  • 获奖情况:
  • 2005-2006年度、2007-2008年度两次荣获中华预防医...
  • 国内外数据库收录:
  • 中国中国科技核心期刊
  • 被引量:34920