中文摘要：

目的探讨哈萨克族人群血清25-羟维生素D〔25（OH）D〕与代谢综合征（MS）的关系。方法2013年11月2—11日,采用多阶段抽样法在新疆阜康市选取18岁以上哈萨克族居民641例为研究对象,对其进行横断面调查,包括形体测量和检测血脂、空腹血糖、25（OH）D、血钙、血磷、碱性磷酸酶（ALP）。MS诊断采用国际糖尿病联盟（IDF）标准。结果哈萨克族人群MS检出率为47.4%（304/641）。与非MS组相比,MS组血清25（OH）D水平低〔（16.47±7.35）μg/L比（18.64±8.65）μg/L〕,差异有统计学意义（P〈0.05）。将25（OH）D水平按四分位分成4组,随着25（OH）D水平的升高,MS的检出率逐步降低,分别为54.4%（87/160）、52.8%（85/161）、41.3%（66/160）、41.3%（66/160）,差异有统计学意义（P〈0.05）。Logistic回归分析结果显示,校正代谢综合征组分（血压、血糖、血脂）及血钙、血磷、ALP等后,25（OH）D水平对MS发生的影响仍有统计学意义〔OR=0.964,95%CI（0.936,0.992）,P〈0.05〕。结论哈萨克族人群血清25（OH）D水平低,且25（OH）D是MS发生的独立保护因素。

英文摘要：

Objective To investigate the relationship between serum 25 -hydroxyvitamin D〔25 （ OH ） D〕and metabolic syndrome（ MS）in Kazak ethnic population. Methods A cross -sectional survey was conducted on a total of 641 Kazak ethnic residents aged over 18 years in Fukang in Xinjiang Uyghur Autonomous Region from November 2 ,2013 to November 11,2013 . The subjects were selected using multistage sampling method. The survey content included body measurements and concentrations of serum lipids,fasting glucose,25（OH）D,blood calcium,serum phosphorus and alkaline phosphatase （ALP）. MS was identified using the International Diabetes Federation（IDF）criteria. Results The detection rate of MS was 47. 4%（304/641）. Compared with the non-MS group,the level of serum 25（OH）D of MS group was lower〔（16. 47 ±7. 35）μg/L vs. （18. 64 ±8. 65）μg/L,P﹤0. 05〕. The level of 25（OH）D was divided into four grades by quartiles. The detection rate of MS decreased with the upgrading of 25（OH）D level,with 54. 4%（87/160）,52. 8%（85/161）,41. 3%（66/160）and 41. 3%（66/160）for the four grades,and the differences were significant（P ﹤0. 05）. Logistic regression analysis revealed that 25（OH）D level still had significant influence on the incidence of MS〔OR=0. 964,95%CI（0. 936, 0. 992）,P﹤0. 05〕after adjusting MS components（ blood pressure,blood glucose,blood lipid）,calcium,phosphorus and alkaline phosphatase. Conclusion Serum 25（OH）D is at a low level in Kazak ethnic MS patient,and serum 25（OH）D level may be an independent protective factor for MS prevalence in Kazak ethnic population.