近年来人们对热疗与肿瘤免疫关系的认识已经深入到分子水平。热疗引起肿瘤细胞免疫原性的变化,免疫细胞数量、分布及活性的变化,热休克蛋白表达的增加以及细胞因子分泌变化的研究取得进展。
Hyperthermia is a fast developing therapy,following the surgery, radiotherapy, chemotherapy and biological treatments. Currently, the researches continue to further and deepen to the molecular level. Hyperthermia induces the changes of immunogenicity of the tumor cells, the alterations of quantity, distribution and the activity of the immunologic cells, augmentation of the heat shock proteins expression and changes of the secration of cytokines. All these researches have made great progress.