目的描述孕妇妊娠早期心理社会应激流行特征及其影响因素,为妇女孕期心理卫生保健提供循证依据。方法选择2011年5月—2013年4月在安徽省合肥市第一人民医院进行孕产期保健3 826名孕27周以前的孕妇作为随访调查对象,分别采用《妊娠相关焦虑量表》、《爱丁堡产后抑郁量表》以及《妊娠期生活事件问卷》评价孕妇妊娠早期的妊娠相关焦虑、生活事件和抑郁发生情况。结果 3 826名孕妇妊娠早期妊娠相关焦虑、抑郁和生活事件阳性检出率分别为30.4%、32.7%和9.3%;多因素logistic回归模型分析结果显示,完全意外怀孕(OR=2.355,95%CI=1.902-2.916)以及非初次怀孕(OR=1.176,95%CI=1.017-1.361)均为妊娠早期孕妇发生妊娠相关焦虑的危险因素,年龄25-29岁(OR=0.814,95%CI=0.675-0.981)、30-50岁(OR=0.706,95%CI=0.553-0.903)以及家庭月收入为5 000-10 000元(OR=0.833,95%CI=0.711-0.976)为妊娠早期孕妇发生妊娠相关焦虑的保护因素;完全意外怀孕(OR=1.487,95%CI=1.202-1.841)为妊娠早期孕妇发生抑郁症状的危险因素,家庭月收入为5 000-10 000元(OR=0.791,95%CI=0.679-0.923)以及文化程度为高中或中专(OR=0.761,95%CI=0.599-0.967)、大专(OR=0.729,95%CI=0.570-0.930)或本科及以上(OR=0.917,95%CI=0.544-0.951)为妊娠早期孕妇发生抑郁症状的保护因素;完全意外怀孕(OR=2.016,95%CI=1.464-2.775)为妊娠早期产生生活事件应激的危险因素,家庭月收入为5 000-10 000元(OR=0.757,95%CI=0.588-0.974)以及文化程度为本科及以上(OR=0.610,95%CI=0.392-0.949)为其保护因素。结论孕妇妊娠相关焦虑、抑郁及生活事件应激较为普遍,妊娠意愿、妊娠年龄、孕妇文化程度以及是否初孕是孕期心理社会应激的主要影响因素。
Objective To explore psychosocial stress and its influencing factors in the pregnant women of first trimester pregnancy. Methods The participants of the study were 3 826 pregnant women who took prenatal care in the First People's Hospital of Hefei City from May 2011 through April 2013. All participants were asked to complete a selfadministered questionnaire survey to collect information on pregnancy related anxiety,depression and life events in the first trimester of pregnancy before 27 weeks of gestation. Results The detection rate of pregnancy-related anxiety,depression and life events were 30. 4%,32. 7%,and 9. 3%,respectively. The results multivariate logistic regression showed that unplanned pregnancy( odds ratio[OR]= 2. 355,95% confidence interval [95% CI]: 1. 902- 2. 916) and non-first pregnancy( OR = 1. 176,95% CI: 1. 017- 1. 361) were the risk factors of pregnancy-related anxiety; the protective factors of pregnancy-related anxiety were aged 25- 29 years( OR = 0. 814,95% CI: 0. 675- 0. 981),aged 30- 50 years( OR =0. 706,95% CI: 0. 553- 0. 903),and with a monthly familial income of 5 000- 10 000 RMB Yuan( OR = 0. 833,95%CI: 0. 711- 0. 976). The risk factor of depression was unplanned pregnancy( OR = 1. 487,95% CI: 1. 202- 1. 841) and the protective factors were with a monthly familial income of 5 000- 10 000 RMB Yuan( OR = 0. 791,95% CI: 0. 679-0. 923) and with an education of high school or technical secondary school( OR = 0. 761,95% CI: 0. 599- 0. 967),with an education junior college( OR = 0. 729,95% CI: 0. 570- 0. 930),and undergraduate or above( OR = 0. 917,95% CI:0. 544- 0. 951). Unplanned pregnancy( OR = 2. 016,95% CI: 1. 464- 2. 775) was a risk factor of life event stress in the first trimester of pregnancy and the protective factors were with a monthly familial income of 5 000- 10 000 RMB Yuan( OR = 0. 757,95% CI: 0. 588- 0. 974) and with an education of bachelor degree and above( OR = 0. 610,95% CI: 0. 392- 0. 949). C