目的:观察中药内外合治溃疡性结肠炎的临床疗效。方法:选取溃疡性结肠炎患者lOO例,随机分为观察组和对照组,每组50例。对照组给予口服柳氮磺胺吡啶配合庆大霉素、黄连素灌肠治疗,观察组给予中药内服配合中药灌肠的中药内外合治疗法治疗。结果:观察组有效率为92%,对照组有效率为66%,观察组优于对照组(P〈0.05);观察组黏液便、脓血便消失时间和腹泻次数恢复正常时间均优于对照组(P〈0.05);观察组治疗时间、住院费用、患者满意度均优于对照组(P〈0.05);两组不良反应发生率比较,无统计学差异(P〉0.05);观察组复发率明显低于对照组(P〈0.05)。结论:中药内外合治溃疡性结肠炎疗效显著。
Objective: To observe the clinical effects of internal and external therapy of Chinese medicine on ulcerative colitis (UC). Methods: 100 cases with UC were randomized into observation group and control group, with 50 cases in each group. Control group were orally given Salazosulfapyridine combined with enema treatment of Gentamicin and Berberine. Observation group were given oral administration of Chinese medicine combined with enema treatment as internal and external therapy of Chi- nese medicine. Results: The effective rate of observation group (92%) was higher than that of control group (66%) ( P 〈 0. 05). The disappearance time of mucus stools, purulent stools and the recovery time of diarrhea were all better than these in control group (P 〈 0.05). The treatment time, hospitalization expenses and the satisfaction of patients in observation group were all better than these in control group ( P 〈 0, 05 ). There was no statistical difference between the adverse reactions of the two groups (P 〉 0.05 ). The relapse rate of observation group was lower than that of control group ( P 〈 0.05 ). Conclusion : Internal and external therapy of Chinese medicine has remarkable therapeutic effects on UC.