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中文摘要：
选用生物相容性好的β-磷酸三钙（β-tricalcium phosphate,β-TCP）、生物活性玻璃（bioglass,BG）及聚乳酸（poly lactic acid,PLA）几种材料进行复合组装,制得了三维多孔结构的骨组织工程支架材料.用模拟体液（simulated body fluid,SBF）进行体外模拟实验.用扫描电镜、X射线衍射、Fourier红外变换光谱及诱导耦合等离子体发射光谱等测试手段,测试分析浸泡不同天数的材料的显微结构、降解性能及反应产物.用Archimedes法和氮气吸附法测定材料的气孔率和比表面积.结果表明,在相同的气孔率条件下,支架材料的降解速率由快到慢依次为：β-TCP/BG/PLA＞β-TCP/BG＞β-TCP.支架材料浸泡在SBF中,表面会生成一层类骨羟基磷灰石层.
英文摘要：
Bioactive composites based on β-tricalcium phosphate （β-TCP）, bioglass （BG） and poly lactic acid （PLA） were prepared. The microstructure, degradability and reaction products of the scaffold soaked in a simulated body fluid （SBF） for different days were characterized through a scanning electron microscope, X-ray diffraction, Fourier transform infrared spectroscopy, and induced coupled plasma spectroscopy. The porosity and specific areas were characterized by the Archimedes＇ method and nitrogen gas adsorption. The results show that at the same porosity, the degradability of the scaffold samples decrease as follows： fl-TCP/BG/PLA〉 β-TCP/BG〉β-TCP. The materials have highly bioactive responses to the SBFand promptly induce a bone-like hydroxyapatite layer on the surface of the scaffolds when immersed in the SBF.
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