按合成方法综述了手性α-氨基酸的研究进展。简要介绍了手性拆分、L-氨基酸的高同系化、不对称烷基化、溉胺的不对称烷基化、脱氢氨基酸的不对称氢化等各种合成方法,对手性α-氨基酸合成的今后发展方向做了讨论。
Research progresses of chiral α-amino acids according to their synthetic methods are reviewed here. Various synthetic methods,such as chiral resolution, homology of L-amino acids,asymmetric alkylation,asymmetric alkylation of imines, and asymmetric hydrogenation of dehydroamino acids, introduced briefly. The developing tendency of synthesis of α-amino acids is discussed.