中文摘要：

作为一个其他的方法，有 Fourier 变换团 spectrometry (MALDI-FTMS ) 的帮助矩阵的激光解吸附作用 / 电离成功地被用来检测并且鉴别自由的基与与 5,5-dimethylpyrroline N 氧化物(DMPO ) 套住的氢氧根和 2-cyano-2-propyl 激进分子的小分子的重量使内收。由 MS/MS 的察觉和鉴定用持续 offresonance 照耀试验导致碰撞的分离(SORI首领)[(DMPO+卑剁愠慮祬楳?湯猠硩整湥???档潬潲祰楲??汹敭桴汹浡湩?木'獞e潮捡祲慬整挠浯潰湵獤眠獡瀠牥潦浲摥甠楳杮???洠瑥潨?潴攠灸慬湩琠敨渠瑡牵?景椠瑮牥捡楴湯?敢睴敥?桴?潣灭畯摮?湡??瀠潲整湩。

英文摘要：

As an alternative method, matrix-assisted laser desorption/ionization with Fourier transform mass spectrometry （MALDI-FTMS） has been successfully used to detect and identify free radical adducts with small molecular weights of hydroxyl and 2-cyano-2-propyl radicals trapped with 5,5-dimethylpyrroline N-oxide （DMPO）. The detection and identification by MS/MS experiments using sustained offresonance irradiation collision-induced dissociation （SORI-CID） of [（DMPO＋·OH-·H）＋H^＋] （m/z 130.0868） and [DMPO＋2 ·CH（CH3）2CN＋H^＋] （m/z 250.1917） have demonstrated that MALDI-FTMS could be an effective method for detection and identification of free radical adducts. Other radical adducts have been also detected and identified. The approach of MALDI-FTMS is simple, fast, and sensitive which has potential for high-throughput analysis.