胀亡(oncosis)是一种特殊形式的非凋亡性细胞死亡方式,它的特征性表现为细胞肿胀、起泡、细胞器肿胀、细胞膜通透性增加和核溶解。细胞胀亡在肿瘤发生发展过程中具有重要作用,明确细胞胀亡在肿瘤发生发展过程中的作用将有助于抗肿瘤研究的深入。
Oncosis is a special kind of non-apoptotic cell death mode, it is characterized by cell swelling, budding, organelle swelling, increased cell membrane permeability and caryolysis. Oncosis has an important role in tumorigenesis, and making its role clear may help us understand the anti-tumor research.