中文摘要：

基因治疗成功的关键技术之一是研制出安全高效的基因转染载体。多功能信封式纳米载体具有易进入细胞、低毒性、低免疫原性、低致瘤性、易制备、转染效率高等优点,是一种有良好应用前景的基因转染载体。综述了近年来多功能信封式纳米载体的研究进展。

英文摘要：

One of the major keys for successful gene therapy is to developing safe and high effective gene delivery vectors.Multifunctional envelope-type nano device（MEND）has shown a promising perspective in gene delivery systems,because of its easy cellular uptake,low-toxic,non-immunogenic,non-oncogenic,easy-to-produce and high transfection activity properties.Recent progress of MEND were reviewed.