中文摘要：

炎症在心血管疾病（cardiovascular disease,CVD）的各个阶段中均发挥着重要作用。C-反应蛋白（C-reactive protein,CRP）是一种典型的人类急性期蛋白,由5个相同的亚基构成,在临床上被广泛用作炎症的非特异性标识物。近年的研究显示,CRP不仅是CVD发病风险的灵敏标识,而且直接参与调控与CVD相关的炎症过程。基于对已有研究发现的回顾和分析,文章指出CRP的单体形式（monomeric CRP,mCRP）是调控局部炎症过程的主要CRP异构体。

英文摘要：

Inflammation plays a critical role in all stages of cardiovascular disease （CVD）. C-reactive protein （CRP） is a typical human acute phase protein composed of five identical subunits. Althought it is routinely used as a non-specifc marker of ongoing inflammation, its role as both a sensitive predictor and an active participator in CVD has been emerging. In this paper, the authors review the recent advances of CRP research and emphasize a key contribution of monomeric CRP （mCRP） in regualting various aspects of local inflammatory processes.