夜间高血压是指夜间平均血压≥120/70 mm Hg(1 mm Hg=0.133 k Pa),其患病率较高,对心、脑、肾的损害较日间高血压更大。导致夜间血压升高的因素众多,以胰岛素抵抗、睡眠呼吸暂停为主。已有相关临床研究证实,夜间服用肾素-血管紧张素-醛固酮系统(RAAS)阻滞剂是降低夜间高血压的有效方法之一。本文从夜间高血压的流行病学、靶器官损害、影响因素、治疗方面进行论述,旨在提示全科医生关注夜间高血压及其影响因素,选择合理的治疗方案。
Nocturnal hypertension( NH),with an average nighttime blood pressure ≥120 /70 mm Hg( 1 mm Hg =0. 133 k Pa) and a high prevalence,injures heart,brain and kidney more than daytime hypertension. There are a lot of factors leading to NH,but the main ones are insulin resistance,sleep apnea. Relevant clinical studies have proved that taking rennin-angiotensin- aldosterone system( RAAS) blockade during night is one of the effective methods to reduce NH. This paper reviews the epidemiology,target organ damage,influencing factors and treatment of NH,to suggest GPs paying attention to NH and its influencing factors to choose reasonable therapeutic regimens.