中文摘要：

热休克蛋白70（HSP70）广泛存在于细胞中,在应激刺激后过表达,可以参与蛋白质的合成及受损蛋白的修复。HSP70在肝癌治疗中的作用日益受到重视：利用其特异性和免疫原性,靶向治疗肝癌。并且可以利用其“分子伴侣”的特点,作为肝癌疫苗,诱发机体抗肝癌的免疫反应。HSP70在肝癌治疗中已初显成效,但也存在很多问题,需要更加深入的研究。总之,HSP70在肝癌治疗中有很大的应用前景。

英文摘要：

Heat shock protein 70 （HSP70）exists in cells, and is highly expressed in response to stress. It al so plays an important role in composing and repairing the protein. The function of HSP70 in hepatocellular immuno- therapy is becoming more and more important： Because of the specificity, immunogenicity and being molecular chaperone, HSP70 can induce the immune responses. But it also has many questions which are needed to research for. In a word, HSP70 is a good molecule in the therapy of hepatocellular carcinoma.