中文摘要：

背景为从繁体中文药屏蔽 bioactive 部件的常规过程费时间、昂贵、低 efficient.Therefore ，一些其他的策略是需要的 urgently.A 小说方法因为从含油树脂的屏蔽反血小板聚集部件用鸡血小板被开发摘录和高效液体 chromatography.Methods 含油树脂的反血小板聚集部件与鸡 thr 的受体，隧道和酶被相结合

英文摘要：

Background The conventional procedure for screening bioactive components from traditional Chinese medicine is time-consuming, expensive and low efficient. Therefore, some alternative strategies are needed urgently. A novel method for screening anti-platelet aggregation components from oleoresins was developed using chicken thrombocyte extract and high performance liquid chromatography. Methods The anti-platelet aggregation components of oleoresins were combined with receptors, channels and enzymes of chicken thrombocytes under physiological environment. Unbound substances were washed away and bound compounds were eluted using specific phosphate buffered solution （PBS）. Compounds released from target sites were collected and analyzed by high performance liquid chromatography and LC-MS. The activity of three compounds which were screened from this model was confirmed using platelet aggregation pharmacology in vivo. Results There were four typical compounds that bound to the thrombocytes： 6-gingerol, 8-gingerol, 6-shogaol and 10-gingerol, and all had shown anti-platelet aggregation activities. Eight-gingerol displayed the best anti-platelet aggregation effect. Conclusions Chicken thromobcyte extract can be used to isolate chemicals that are ligands of the receptor or other bio-targets on the platelet. This may therefore be a simple and efficient method to screen for anti-platelet aggregation compounds from traditional Chinese medicine.