中文摘要：

驱动蛋白的颈链是驱动蛋白力产生的关键元件。颈链与驱动蛋白马达结构域的对接过程为驱动蛋白沿着微管的向前运动提供了驱动力。驱动蛋白的颈链由14～18个氨基酸组成，它连接着马达结构域和由缠绕螺旋组成的茎部。颈链与驱动蛋白马达结构域的对接过程是通过多种弱键相互作用实现的，这些弱键相互作用多数都直接或间接与水分子有关。颈链及其相关区域的极为巧妙的氨基酸结构使得这些弱键能够在细胞环境下有效地发挥作用。对颈链的结构与功能关系的认识大大提高了我们对驱动蛋白运动机制的理解。

英文摘要：

Kinesin＇s neck linker is one of the most important mechanical elements for its force-generating mechanism. The docking process of neck linker to the motor domain provides the driving force for the forward motion of kinesin along microtubule. Neck linker is a region of roughly 14-18 amino acids that links the motor domain and coiled-coil stalk. The docking process of neck linker to the motor domain is achieved via various non-bonding interactions, most of which have direct or indirect relations with water. The highly exquisite amino acid structures of neck linker and its related regions make those non-bonding interactions play their roles in eytoplastic environment effectively. The knowledge of the structure-function relationship of kinesin＇s neck linker largely deepens the understanding of kinesin mechanism.