脑微血管内皮细胞不仅仅具有屏障特性,而且还具有多种分泌功能,因此微血管内皮细胞的损伤与脑血管疾病的发生、发展有着密切的关系,也为研究中药防治脑血管疾病的机制提供了基础。近年来,围绕中药减轻脑血管疾病过程中微血管内皮细胞损伤,展开了很多研究。仅从细胞的屏障特性、细胞氧化损伤、细胞的分泌功能等几个方面综述了中药对体外培养脑微血管内皮细胞影响的研究进展。
The brain microvascular endothelial cells have a lot of characters, they not only act as an barrier, but also can se- crete much cytokine. So there may be a close relationship between the injury of the BMEC and the occurrence,development of the cerebrovascular disease,and also offers a basis for the mechanism of the therapy of the cerebrovascular disease by the TCM. In re- cent years,more and more researchers begin to pay attention to the effect of the traditional Chinese medicine (TCM) in the dam- age of the microvascular endothelial cell in the cerebrovascnlar disease. This text overviews the advancement of the effect of the TCM on the BMEC, from the different aspects of the barrier character, excrete character, et al.