中文摘要：

目的比较不同施灸频度温和灸对亚健康状态疗效的影响,探讨艾灸调治亚健康状态的有效性和量效关系。方法选取受试者108例,采用随机数字表法随机分为Ⅰ组（36例）、Ⅱ组（36例）和Ⅲ组（36例）。每组所选穴位相同,均为关元、足三里（双侧）、三阴交（双侧）,将艾条一端点燃,对准应灸的穴位,距皮肤3~4 cm施灸,以受试者局部皮肤有温热感而无灼痛为宜。每穴灸10 min,以皮肤潮红为度。3组分别采取每日灸、隔日灸、每星期灸,施灸1个月为1个疗程,连续2个疗程。治疗前后分别观察亚健康症状积分量表,免疫球蛋白Ig A、Ig M、Ig G与超氧化物歧化酶（SOD）,进行统计学分析。结果Ⅰ组总有效率为87.9%,Ⅱ组总有效率为84.8%,Ⅲ组总有效率为34.3%。3组组间两两比较,Ⅰ组与Ⅱ组比较不具有统计学差异（P〉0.05）,Ⅰ组、Ⅱ组分别与Ⅲ组比较差异具有统计学意义（P〈0.05）。Ⅰ组和Ⅱ组治疗后Ig A、Ig M、Ig G及SOD均有增加,具有统计学意义（P〈0.05）,Ⅲ组治疗后无明显上升（P〉0.05）。结论温和灸调治亚健康状态的疗效与灸频有关,每日灸与隔日灸疗效显著,优于每星期灸。

英文摘要：

Objective To compare the effects of mild moxibustion at different frequencies on sub-health state,and to discuss the effectiveness and dose-response relationship of moxibustion in treating sub-health state.Method Totally 108 subjects were divided by using random number table into group Ⅰ（36 cases）,group Ⅱ（36 cases）and group Ⅲ（36 cases）.Same acupoints were selected for the three groups,including Guanyuan（CV3）,bilateral Zusanli（ST36）,and bilateral Sanyinjiao（SP6）.A moxa stick was ignited at one end to treat the corresponding points,3-4 cm away from the skin,making the topical area hot but without burning pain.Each point was treated for 10 min,till the skin flushed.The 3 groups were respectively treated once a day,once every other day,and once a week,1 month as a treatment course,totally for 2 courses.The Sub-health Symptoms Scale,immunoglobulins Ig A,Ig M and Ig G,and superoxide dismutase（SOD）were evaluated and statistically analyzed before and after intervention.Result The total effective rate was 87.9% in group Ⅰ,84.8% in group Ⅱ,and 34.3% in group Ⅲ.The paired comparisons showed that there was no significant difference between group Ⅰ and Ⅱ（P〉0.05）,while group Ⅰ and group Ⅱ were both significantly different from group Ⅲ（P〈0.05）.After intervention,the levels of Ig A,Ig M,Ig G,and SOD were significantly increased in group Ⅰ and Ⅱ（P〈0.05）,but the increases in group Ⅲ were statistically insignificant（P〉0.05）.Conclusion The therapeutic efficacy of mild moxibustion for sub-health is related to the treatment frequency,and frequencies at once a day and once every other day both can produce significant efficacies,which are superior to that of moxibustion at once a week.