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肝切除联合微波固化治疗BCLC-B期肝细胞癌的生存预后分析
  • ISSN号:1007-631X
  • 期刊名称:《中华普通外科杂志》
  • 时间:0
  • 分类:R735.7[医药卫生—肿瘤;医药卫生—临床医学]
  • 作者机构:第四军医大学唐都医院普通外科,西安710038
  • 相关基金:国家自然科学基金面上基金资助项目(81172287)
中文摘要:

目的探讨肝切除联合术中微波固化或经导管肝动脉栓塞(transcatheter arterial chemoembolization,TACE)对BCLC—B期肝细胞癌患者生存预后的影响。方法回顾性分析172例BCLC.B期患者资料,分为2组,分别接受手术联合微波固化(liver resection combined with microwave coagulation therapy,LR+MCT)组,107例及接受TACE治疗组,65例。分别比较2组患者术后30d的死亡率、中位生存期、近远期生存率及并发症等。结果2组患者院内死亡率比较差异无统计学意义(χ2=0.285,P=0.593),但LR+MCT组术后有更高的并发症发生率(χ2=4.694,P:0.03)。LR+MCT组比TACE组的总体中位生存期长,差异有统计学意义(r=9.135,P=0.003),但2组5年生存期差异无统计学意义(χ2=4.767,P=0.434)。结论微波固化联合肝切除术和TACE是一样安全,并且手术组能够获得更长的中位生存期和较高的早期生存率。

英文摘要:

Objective To explore the prognosis of patients with BCLC-B hepatocellular carcinoma (HCC) receiving LR + MCT vs TACE. Methods BCLC-B HCC patients undergoing LR + MCT ( 107 cases) and TACE (65 cases) were retrospectively evaluated, in terms of 30-day mortality rate, the median survival, early and long term survival rate and complications. Results The hospital mortality rate was similar between the two groups (χ2 = 0. 285, P = 0. 593 ). However, the LR + MCT group were with a significantly higher postoperative complication rate than the TACE group (χ2 = 4. 694, P = 0.03 ). At the same time, the LR + MET group had significantly higher median survival rates (χ2 = 9. 135, P = 0. 003 ), but, there was no statistical difference for five-year survival (χ2 = 4. 767, P = 0. 434 ). Conclusions LR + MCT are as safe as TACE for patients with BCLC-B HCC, and it provides longer median survival rates.

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期刊信息
  • 《中华普通外科杂志》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中华医学会
  • 主编:
  • 地址:北京市阜内大街133号
  • 邮编:100034
  • 邮箱:zhpw@cjgs.com.cn
  • 电话:010-66124704 66162070
  • 国际标准刊号:ISSN:1007-631X
  • 国内统一刊号:ISSN:11-3855/R
  • 邮发代号:82-222
  • 获奖情况:
  • 国内外数据库收录:
  • 日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版),中国北大核心期刊(2000版)
  • 被引量:33517